An Orbital Malignant Melanoma Arising in Cellular Blue Nevus in a Patient with Nevus of Ota
نویسندگان
چکیده
Melanomas arising from orbital melanocytic proliferations are exceedingly rare. Many questions remain regarding their development and malignant transformation. We report on a 45-year-old Caucasian woman with a nevus of Ota that presented with visual disturbances involving her right eye and was found to have a biopsy-proven cellular blue nevus in the orbital space. Five years later, she presented with proptosis and worsening symptoms. Biopsy at that time showed a cellular blue nevus with areas of melanoma. We conclude that patients with a nevus of Ota or an orbital cellular blue nevus, particularly Caucasians, should be monitored for ocular/orbital involvement and followed closely for signs of rapid growth. There may be a progressive evolution to melanoma from a blue nevus.
منابع مشابه
Meningeal melanomas associated with transforming Ota nevus to malignant melanoma: a case report
Absract Intracranial invasion of cellular blue nevus (CBN) from the skin is extremely rare and such a condition with malignant transformation is even rarer. A case of meningeal melanoma with malignant transformation which was derived from an Ota nevus is presented in this report. A21-year-old man with a neurocutaneous syndrome since childhood was referred with headache and mild le...
متن کاملA malignant melanoma associated with a blue nevus of the lip.
Blue nevi are characterized by a collection of pigment-producing melanocytes in the dermis. These lesions clinically present as well demarcated cerulean-blue or bluish black colored papules or plaques that usually measure less than 1 cm in diameter. They are typically found on the dorsal surface of the hands and feet or in the head and neck region; however, they are rarely found in the oral cav...
متن کاملPrimary orbital melanoma in association with cellular blue nevus.
PURPOSE To describe 3 cases of primary orbital melanoma associated with either known or subsequently discovered cellular blue nevus. METHODS The clinical records and surgical specimens of 3 patients who underwent orbital exenteration for primary orbital melanoma and who had a cellular blue nevus diagnosed before or after detection of the melanoma were retrospectively reviewed. RESULTS All 3...
متن کاملBilateral congenital nevus of Ota in association with Mongolian spot
A 24-year-old woman presented with asymptomatic hyperpigmented bilateral patches on her temples, eyelids and forehead since birth. Furthermore, the patient had a congenital grey patch, compatible with Mongolian spot, on her buttock. She had no vascular or other cutaneous lesion. Histopathologic examination revealed bipolar dendritic melanocytes dispersed in a ribbon-like pattern between the col...
متن کاملAtypical cellular blue nevus or malignant blue nevus?*
Blue nevus is a benign melanocytic lesion whose most frequent variants are dendritic (common) blue nevus and cellular blue nevus. Atypical cellular blue nevus presents an intermediate histopathology between the typical and a rare variant of malignant blue nevus/melanoma arising in a cellular blue nevus. An 8-year-old child presented a pigmented lesion in the buttock since birth, but with progre...
متن کامل